CELL AND MOLECULAR BIOLOGY
Unit I |
| Ultra structure of a plant
and animal cell |
| Cell wall structure and
functions |
| Plasma membrane |
| membrane models |
| Unit membrane |
| fluid mosaic |
| membrane
transport |
| membrane transport |
| Introduction to signal
transduction and other functions. |
| Unit II |
| Ultra structure and
functions of subcellular organelle |
| Mitochondria |
| Endoplasmic reticulum |
| Golgi complex |
| Lysosomes |
| Chloroplast |
| Unit III |
| REPLICATION OF DNA |
| Nucleic acids as carriers
of genetic information carriers |
| Nucleosomes: organization
of DNA |
| Semi conservative method:
mechanism |
| experimental evidence |
| Enzymology of DNA
replication |
| events at the replication
fork |
| rolling circle method of
DNA replication |
| Inhibitors of DNA
replication. |
| Unit IV |
| TRANSCRIPTION |
| initiation |
| elongation |
| termination |
| inhibitors of
transcription |
| antisense RNA |
| Post transcriptional
processing of eukaryotic mRNA |
| TRANSLATION |
| The genetic code and its
features |
| Ribosome structure |
| Charged tRNA |
| F.met-tRNA |
| initiator codon |
| Shine – Dalgarno sequence |
| formation of initiation
complex |
| role of EF – Tu |
| role of EF – Tu |
| Ef-Ts |
| Ef-g |
| GTP |
| non sense codons |
| release factors- RF1 and
RF2. |
| Protein synthesis in E.
coli |
| Transcription –
translation coupling in prokaryotes |
| post translational
modification of protein |
| Unit V |
| GENE REGULATION: |
| Enzyme induction |
| repression |
| operon concept |
| Lac-operon |
| trp operon |
| co-ordinate regulation |
| positive and negative
regulation |
| DNA repair light repair,
dark repair |
| Repair systems in
E.coli.Excision |
| Repair systems in
E.coli recombination |
